منابع مشابه
Circulating cancer cells.
Circulating tumour cells (CTCs) can be detected in the blood of many patients with different types of early or advanced cancer using antibody-based assays or molecular methods. In many studies the detection and quantification of CTCs has been linked to unfavourable prognosis. CTC detection offers the opportunity for individualized risk assessment beyond that determined by TNM staging. However, ...
متن کاملCirculating tumor cells: liquid biopsy of cancer.
BACKGROUND The detection and molecular characterization of circulating tumor cells (CTCs) are one of the most active areas of translational cancer research, with >400 clinical studies having included CTCs as a biomarker. The aims of research on CTCs include (a) estimation of the risk for metastatic relapse or metastatic progression (prognostic information), (b) stratification and real-time moni...
متن کاملCirculating Tumor Cells in Prostate Cancer
Circulating tumor cells (CTCs) can provide a non-invasive, repeatable snapshot of an individual patient's tumor. In prostate cancer, CTC enumeration has been extensively studied and validated as a prognostic tool and has received FDA clearance for use in monitoring advanced disease. More recently, CTC analysis has been shifting from enumeration to more sophisticated molecular characterization o...
متن کاملCirculating tumor cells of colorectal cancer
As the prognosis of colorectal cancer (CRC) patients is mostly determined by the occurrence of distant metastases, circulating tumor cells (CTC) may be an attractive therapeutic target. Despite the rarity of CRCderived CTC, considerable progress has recently been made in the investigation of their molecular characteristics. In this review article we present recent clinical and molecular data on...
متن کاملCirculating tumour cells in breast cancer--review.
Disseminated malignancies are responsible for the majority of cancer-related deaths. During the metastatic process, circulating tumour cells (CTCs) are generated. The presence of CTCs, epithelial cells found in the peripheral blood, is an essential step in establishing distant metastases. Circulating epithelial cells have the morphology of malignant cells and their number in the blood correlate...
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ژورنال
عنوان ژورنال: BMJ
سال: 1964
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.1.5399.1683